Current trends in designing antiviral agents against emerging and re-emerging RNA viruses

RNA viruses have always been a great threat to human civilization, and these have evolved along with humanity's progress. In parallel, this large group of viruses constitutes a great challenge for humankind, which is not yet properly prepared for. The most indisputable proof for this fact is verified in the COVID-19 pandemic (SARS-CoV-2), which resulted in immeasurable economic impacts, as well as thousands of deaths worldwide. Still, other viruses were able to leave their negative marks on the history of our modern society, such as Hepatitis C (HCV), Influenza (INFV), HIV, Ebola (EBOV), Marburg (MARV), Zika (ZIKV), MERS- and SARS-CoV, among others.